An ancient urn is found in a cemetery outside Rome. Once opened, it triggers a series of violent incidents: robberies, rapes and murders increase dramatically, while several mysterious, evil-looking young women coming from all over the world are gathering in the city. All these events are caused by the return of Mater Lacrimarum, the last of three powerful witches who have been spreading terror and death for centuries. Alone against an army of psychos and demons, Sarah Mandy, an art student who seems to have supernatural abilities of her own, is the only person left to prevent the Mother of Tears from destroying Rome.
Elena, a young trainee psychiatrist, dreams of bringing "mad" people back to a normal life; she makes them talk, she provokes and incites them in the hope of finding the distinguishing signs of normality. Fausto is a boy judged "mad", who has been hospitalized against his will several times, an extrovert musician, he shows clear signs of normality.
Amos, a watchmaker, loses his wife due to post-surgery complications. Destroyed by grief, he joins old friends Karl and Maner, former revolutionaries, to kidnap Prime Minister Ullmann, once their companion, to extort money from the state.
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